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tBID, a membrane-targeted death ligand, oligomerizes BAK

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Aug 15, 2000 · BID is a member of the BH3-domain-only subgroup of BCL-2 family members proposed to connect proximal death and survival signals to the core apoptotic pathway at the level of the classic family members that bear multiple Bcl-2 homology (BH) domains (Adams and Cory 1998; Gross et al. 1999a).This set of pro-apoptotic proteins shares their only sequence homology within the BH3 …

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